A number of previously identified targets of Snail (i.e., TNFA, CCL2, CCL5, FN1, THBS1, NDRG1, KLF4, EGFR, RAB25, PKP2, PFKP, TBP, CD44, and IL-8) were selected because of their potential in tumor progression [11, 26, 27]. This evidence concerns the gene KLF4 and neoplasm.