ITGB2 and neoplasm: In animals injected with CD18/HPAF cells, we observed no significant changes in mice weight (Additional file 2: Figure S4A) and tumor weight (Additional file 2: Figure S4B), but increase in the number of liver macrometastases (p = 0.0083, Additional file 2: Figure S4C) as well as liver micrometastasis (p = 0.0083, Additional file 2: Figure S4D) in mice injected with CD18/HPAF-shSEMA5A than CD18/HPAF-Control cells.