In a similar model of obesity, the use of cagaita extracts at 7 and 14 mg gallic acid equivalent for 8 weeks protected against dyslipidemia, fasting hyperglycemia, and further attenuated both hepatic gluconeogenesis and inflammation as observed by the expression of TNF-α and transcriptional factor NF-κB [19]. Here, TNF is linked to obesity due to melanocortin 4 receptor deficiency.