PTAFR and familial pancreatic carcinoma: Considering the important roles of PAF-R in augmenting the growth and/or impeding the efficacy of cancer therapies in several experimental tumor model systems [3,4,5,6,7,8,9,10,11], the current studies determined the potential role and mechanism of functional PAF-R in mediating gemcitabine-induced MVP release in pancreatic cancer cells.