SLC7A5 and cancer: Importantly, the anomalous upregulation of LAT1 activity has been demonstrated in several types of cancer, such as breast cancer, pancreatic cancer, prostate cancer, non-small cell lung cancer, esophageal squamous cell carcinoma, colorectal, head, and neck cancer and gliomas [6,7,8,9,10,11,12,13,14,15].