TP53 and embryonal carcinoma: Overall, our results, where single agent 5-aza was equally effective in both p53-deficient (NCCIT) and proficient (2102Ep) isogenic in vitro models of cisplatin-resistant GCTs, are in line with those reported for the treatment of the embryonal carcinoma cell line NT2/D1 and its resistant subline NT2/D1-R1 with either decitabine or guadecitabine.