LMO2 and acute lymphoblastic leukemia: Focusing on the functional significance of an 8-bp heterozygous insertion at the LMO2 locus in the T-ALL cell line MOLT4, they identified TF binding and enhancer activity, driving heterozygous expression of LMO2. These findings were further reported in two more T-ALL cell lines, six paediatric and nine adult T-ALL patients [57].