We analyzed PNPLA3 rs738409 (C/G), MTP493 rs1800591 (G/T), and TM6SF2 rs58542926 (C/T), which are known to be associated with liver steatosis/nonalcoholic steatohepatitis and/or lipid metabolism. This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatohepatitis.