GPT and congenital secretory chloride diarrhea 1: However, primary care, which is ideally positioned to identify patients at risk of CLD, still largely relies on standard liver function tests (LFTs); namely alanine transaminase (ALT) and also ultrasonography, both of which are shown to have little prognostic value in identifying those at an earlier stage of fibrosis who go on to develop progressive disease and cirrhosis [16–18].