On the other hand, FAP-induced airway eosinophilia was markedly impaired in Rag2−/−Il2rg−/− mice, which lack acquired immune cells, innate lymphoid cells (ILCs) and IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21, compared with wild-type mice (Fig. 4b), suggesting that ILCs and/or IL-2Rγ-ligands may be important for FAP-induced airway eosinophilia. This evidence concerns the gene IL2RG and Increased total eosinophil count.