In particular, neutrophils, macrophages and lymphocytes, but not eosinophils, were increased in BAL fluids of Rag2−/− mice compared with wild-type mice (Fig. 4a), suggesting that acquired immune cells such as T, B and NKT cells were not essential for FAP-induced airway eosinophilia. This evidence concerns the gene RAG2 and Increased total eosinophil count.