IFNA1 and infection: On the contrary, supernatants from infections with viruses expressing the IFNα/βBPGAGmut, VACVIFNα/βBPGAGmut and ECTVIFNα/βBPGAGmut, acted like those from their corresponding WT viruses and were able to prevent the protective action of IFN-I against VSV (Fig. 3b, left panels).