In search for the mechanism driving hsa-miR-150 down-regulation in CMML monocytes, we first checked MIR150 coding sequence in sorted peripheral blood monocyte DNA collected from 49 CMML patients24 and did not observe any mutation, nor we detected any deletion in 19q13.33 region where MIR150 gene is located. This evidence concerns the gene MIR150 and chronic myelomonocytic leukemia.