Transcriptomic analysis of the CIMP subgroups identified a number of known T‐ALL drivers such as TAL1 (LFC −4.1), TLX3 (LFC 12.2), and NKX2‐1 (LFC 21.5) among the top most significant DEGs (Figure 2C) as well as HOXA9 (LFC 4.6), HOXA10 (LFC 4.8), and MEF2C (LFC 2.4) implicated as differentially expressed (Table S3). This evidence concerns the gene MEF2C and acute lymphoblastic leukemia.