TAL1 overexpression may also occur as a consequence of TAL1‐TCRA/D translocations (~5% of TAL1 expressing T‐ALL),37 or non‐coding microinsertions that generate super‐enhancers.38, 39 In the 30 T‐ALL samples that were RNA‐sequenced, no TAL1‐TCRA/D translocations were observed, but this could be explained by inefficient alignment to the TCR regions in the RNA‐sequencing analysis. This evidence concerns the gene TAL1 and acute lymphoblastic leukemia.