CareStartTM malaria an HRP2-based immunochromatographic test which detects HRP2 antigen that is specific for Plasmodium falciparum has a very high performance level as reported by the most recent mRDT evaluation programme [13] and is among the mRDTs approved for procurement by National Malaria Elimination Programme (NMEP). This evidence concerns the gene HDGFL2 and malaria.