(1) The miR-17-92 cluster is likewise named as human oncomiR-1 and encompasses seven members (miR-17-5p, miR-17-3p, miR-20a, miR-18a, miR-92a, miR-19a, and miR-19b)(2) c-Myc is reported to directly target mir-17-92 cluster, and transcriptional regulation is significantly influenced by expression profile of Myc proto-oncogene(3) Notch and Sonic Hedgehog pathways are also involved in the activation of miR-17-92 in cancer(4) A higher miR-17-5p expression contrarily relates with the survival of lung cancer patients. Here, MYC is linked to cancer.