In humans with acute myeloid leukemia (AML), the MLL gene on 11q23 is fused to the LCX leukemia-associated protein with a CXXC domain gene on 10q22, which was cloned as Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) (12). This evidence concerns the gene TET1 and acute myeloid leukemia.