In humans with acute myeloid leukemia (AML), the MLL gene on 11q23 is fused to the LCX leukemia-associated protein with a CXXC domain gene on 10q22, which was cloned as Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) (12). The gene discussed is KMT2A; the disease is acute myeloid leukemia.