Knockdown in AGS and BGC-823 gastric cancer cell lines inhibited cell migration and invasion via a downregulation of E-cadherin expression (EMT marker) probably via a decrease in TGF-β secretion since the supplementation of exogenous TGF-β restored E-cadherin expression and cell migration and invasion (Liu et al., 2015). Here, TGFB1 is linked to gastric cancer.