RTP3 and cancer: In many cancers, differential regulation of the expression of TMEMs has been observed, such as in lymphomas (TMEM176) (Cuajungco et al., 2012), colorectal cancer (TMEM25) (Hrasovec et al., 2013), hepatic cancer (TMEM7) (Zhou et al., 2007), and lung cancer (TMEM48) (Qiao et al., 2016).