ACKR3 and hepatocellular carcinoma: However, for lung cancer (HR 2.40; 95% CI 0.34–17.07, p = 0.383) (Fig. 4e) and hepatocellular cancer (HR 1.37; 95% CI 0.84–2.24, p = 0.209) (Fig. 4f), no significant relationship was found between CXCR7 expression level and OS of tumor patients.