CD36 and neoplasm: Based on the correlation between the prognosis of breast cancer and CD36 expression in the tumor (Fig. 1a), we determined that high expressing CD36 increased growth and migration of breast cancer cells (Fig. 1e, h, i), while inhibition of CD36 expression resulted in reduction of growth or migration and increase of apoptosis, mainly in ER-positive breast cancer cells (Fig. 1d–i).