According to the GWAS Catalog and Immunobase [18, 19], five of these shared loci (PADI4 at 1p36.13, NAB1 at 2q32.3, COBL at 7p12.1, CCL21 at 9p13.3, and GATA3 at 10p14) have been associated with a single autoimmune disease so far and thus they represent new pleiotropic loci in autoimmunity. This evidence concerns the gene COBL and Autoimmunity.