IL10 and malaria: IL‐10 is a potent anti‐inflammatory cytokine and an important regulator of inflammation‐induced pathology,80 it is therefore no surprise that systemic IL‐10 concentrations are elevated in highly inflammatory diseases such as sepsis81, 82 and malaria.83, 84 More surprisingly, however, circulating IL‐10 is also elevated during mild/uncomplicated83, 85 and asymptomatic/subclinical malaria infections73, 86; indeed these cases may represent successful balancing of inflammation‐mediated parasite control and effective regulation of inflammation by IL‐10.