In early sepsis‐related ARDS, downregulation of TLR1, TLR4 and TLR5 transcripts in mononuclear cells correlates with increased survival 23, whereas in a pulmonary contusion mouse model of lung injury, alveolar neutrophil recruitment is TLR4/MyD88‐dependent 26. The gene discussed is TLR4; the disease is Sepsis.