G6PD and Miyoshi myopathy: Hu et al. (2013) showed that the loss of G6PD expression reduced A375-G6PDΔ cell proliferation in a mouse xenograft model of MM, which is consistent with our observations that the increase in G6PD expression in A375-GAS5si cells (Fig. 6a) coincided with reduced apoptosis (Fig. 3a).