Blind visual rating, without prior knowledge of Aβ or Apolipoprotein E (ApoE) status, of all pseudo-FDG SUVR images (CN, AD, and bvFTD) by a clinical FDG expert (KH) matched the clinical diagnosis in 71% (20/28) of individuals (dementia present, bvFTD, and AD, sensitivity 82.4% (CI 56.6–96.2) and specificity 60% (CI 26.2–87.8). This evidence concerns the gene APOE and dementia.