FPR3 and infection: Leukocyte responses to chemotactic factors or chemoattractants during inflammation are dependent on specific G protein-coupled receptors.1 One class of these receptors is formyl-peptide receptors (FPRs), which include formyl peptide receptor 1 (FPR1), formyl peptide receptor 2 (ALX/FPR2 or FPR2), and formyl peptide receptor 3 (FPR3).2 FPRs facilitate the trafficking of phagocytes to the site of infection, and modulate the survival and the phagocytic activity of infiltrating cells.