Many signaling pathways are thought to be involved in the proliferation and migration of RA-FLSs, including the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway (6), nuclear factor-kappaB (NF-κB) pathway (7), mitogen-activated protein kinases (MAPKs) pathway (8). Here, WNK2 is linked to rheumatoid arthritis.