RBFOX3 and Alzheimer disease: The bar graph in Figure 1I quantifies LPS association with nuclei in the temporal lobe neocortex (see text); in AD over control; this ratio is about 16.3 for the samples examined; to investigate whether LPS-encapsulated AD nuclei were of neuronal or astroglial origin we next counterstained with the neuron-specific green stain NeuN (Figure 2).