Since other studies found that ROR1 is variably expressed on the CLL cells of different patients [22], we examined for expression of cortactin and phosphorylated cortactin in CLL cells that expressed ROR at high levels (ROR1Pos CLL) versus low-to-negligible levels (ROR1Neg CLL). The gene discussed is ROR1; the disease is B-cell chronic lymphocytic leukemia.