We have also noted that, without dihomo-γ-linolenic acid supplementation, the tumor size of the delta-5-desaturase-KD vehicle control group is slightly smaller than that of the delta-5-desaturase-WT vehicle control group (Fig. 4), consistent with the relatively higher concentration of dihomo-γ-linolenic acid, ratio of dihomo-γ-linolenic acid/arachidonic acid, and concentration of 8-hydroxyoctanoic acid (although 8-hydroxyoctanoic acid never reached the threshold level). The gene discussed is FADS1; the disease is neoplasm.