FADS1 and neoplasm: It is noteworthy that dihomo-γ-linolenic acid supplementation resulted in an average tumor size of ~ 178.2 ± 31.9 mm3 in delta-5-desaturase-KD tumors (Fig. 4b), leading to a similar effect compared to 5-FU treatment in delta-5-desaturase-WT tumors (~ 204.3 ± 55.3 mm3, Fig. 4a).