FADS1 and malignant colon neoplasm: Besides having promising outcomes for treatment of colon cancer, we have also demonstrated that dihomo-γ-linolenic acid, along with a genetic delta-5-desaturase knockdown strategy, can suppress the growth, migration, and invasion of many other cancer cells, including pancreatic cancer BxPC-3 [27, 28], breast cancer MDA-MB-231 and 4 T1 [29], lung cancer A549, liver cancer HepG2, and their associated xenograft tumors (unpublished research results).