By comparing our findings to 578 known driver genes from the COSMIC database [30], we found that among the 35 genes, 12 of them are known cancer driver genes (EPHA3, TRIM24, BRAF, LIFR, PTEN, NTRK3, FBXW7, ARID1A, TP53, JUN, CHCHD7, SMAD4). The gene discussed is PTEN; the disease is cancer.