This study also showed that addition of TRP agonists (capsaicinoid as TRPV1 agonist, 150 μM/menthol as TRPM8 agonist, 1 mM or 10 mM/piperine as TRPA1 and TRPV1 agonists, 150 μM or 1 mM) to the bolus decreased the bolus passing time through the pharynx and reduced the swallowing response time and laryngeal penetrations in dysphagia patients [38]. The gene discussed is TRPA1; the disease is Dysphagia.