Recent studies in patients with oropharyngeal dysphagia reported that addition of a natural capsaicinoid (a TRPV1 agonist, 150 μM) to the alimentary bolus improved the efficacy of swallowing and reduced the prevalence of pharyngeal residues and penetrations of bolus particles into the larynx [37]. The gene discussed is TRPV1; the disease is Oral-pharyngeal dysphagia.