In another study in oropharyngeal dysphagia patients, a TRPV1 agonist (capsaicinoid, 150 μM) had a better therapeutic effect on improving swallowing compared with a TRPM8 agonist (menthol, 1 mM or 10 mM) [38]. Here, TRPM8 is linked to Oral-pharyngeal dysphagia.