The capacity of Mbnl1 to rescue the main DM1 symptoms is also observed in the Drosophila DM1 model, where cardiac overexpression of Muscleblind (Mbl), the Drosophila Mbnl1 ortholog, is sufficient to rescue the heart dysfunctions and reduced survival of DM1 flies [29]. The gene discussed is MBNL1; the disease is Steinert myotonic dystrophy.