FTO and diabetic kidney disease: After combining all association data (Stage-1 set-1, set-2 and Stage-2) using the inverse-variance fixed-effects meta-analysis, we found that one SNP locus, rs56094641 in FTO at chromosome (Chr) 16, 16q12.2, showed a genome-wide significant association with diabetic nephropathy (P = 7.74 × 10−10, odds ratio (OR) = 1.23, 95% confidence interval (CI) 1.15−1.31, Table 2 and S2 Table).