PTEN and neoplasm: CNAs were more frequent in tumours from 6 dogs that died within 6 months of diagnosis (although only 4 of the dogs had confirmed metastasis at diagnosis), and specific gene losses (PTEN and FAS; CFA26) and gains (MAPK3, WNT5B, FGF, FOXM1 and RAD51; CFA27) were associated with a shorter survival time [97].