In this study, children with low CRP levels were prescribed antibiotics, although children who were judged as severely ill or highly suspected of having pneumonia were excluded, and despite evidence that CRP levels <5 mg/L can safely rule out serious infections requiring hospitalisation in children.27 Knowledge on the GPs’ reasoning behind these prescriptions, including possible non-medical reasons, might provide further insights to better target interventions for antibiotic stewardship. The gene discussed is CRP; the disease is infection.