JAK2 and myeloproliferative disorder: The Chi square analysis for the association between JAK2 V617F mutation and AT revealed that MPN patients with positive JAK2 V617F mutation seemed to have 2 times (OR = 2.087, 95% CI 1.352, 3.221) the risk of developing AT as compared to those with negative JAK2 V617F mutation (p = 0.001).