The results show that the IFN-γ level in the blood of the siRNA group mice had increased, while the level of the cytokine IL-10 had significantly decreased (p < 0.05) compared with the control group. The PD-L1 level had significantly increased in the tumor, but significantly decreased in the liver compared with the control group (p < 0.05, Fig. 2). The gene discussed is CD274; the disease is neoplasm.