Additionally, data from several other studies of LGALS3-/- mice seem to support the overall conclusions of Beccaria et al., with LGALS3-/- showing overall improved antibody responses in several models of parasite infection, including Plasmodium yoelii (46) and Schistosoma mansoni infection models (37, 45, 47–50), but not Plasmodium berghei and Plasmodium chabaudi infection (46). Here, LGALS3 is linked to parasitic infectious disease.