CXXC4 and type 2 diabetes mellitus: aMSI2 hypomethylated by 11% in T2D cases and 7% in high glucose cases (p-value = 0.038). CXXC4 hypomethylated by 15% in T2D cases (p-value = 0.044), and 12.8% in high glucose cases (p-value = 0.033).bMSI2 hypomethylation significantly correlated with T2D.