Consequently, 15 targets were overlapped, including MMP1, CASP3AKT1, HIF1A, IL10, MMP9, PTGS2, BCL2, BAX,MMP2, PTGS1, SLC6A2, PRKCA, LGALS3, BCHE, which were predicted as the candidate targets for SAL in treatment DKD. Here, IL10 is linked to diabetic kidney disease.