Consequently, 15 targets were overlapped, including MMP1, CASP3AKT1, HIF1A, IL10, MMP9, PTGS2, BCL2, BAX,MMP2, PTGS1, SLC6A2, PRKCA, LGALS3, BCHE, which were predicted as the candidate targets for SAL in treatment DKD. The gene discussed is MMP1; the disease is diabetic kidney disease.