To test this, we examined whether higher levels of tau pathology in the entorhinal cortex (EC) and/or inferior temporal cortex (IT), determined by Flortaucipir (FTP)-PET, were associated with greater loneliness after adjusting for age, sex, APOEε4 status, socioeconomic status, social network, depression, anxiety, and memory function within this CN sample. Here, MAPT is linked to depressive symptom measurement.