Previous reports indicate that EriB can induce leukemia and lymphoma cell apoptosis by increasing intracellular ROS levels and inhibiting NF-κB pathway, previous studies have also confirmed that EriB can block TNF-induced NF-κB activation by inhibiting IκB degradation in acute myeloid leukemia cell line Kasumi-1 cells. This evidence concerns the gene NFKB1 and acute myeloid leukemia.