TAMs from mice bearing Beclin1 knockdown tumors had significantly decreased expression of CD206 and PD-L1, as well as slightly increased expression of CD86 and MHC-II whereas the effect did not achieve statistical significance (Fig. 5b), indicating that loss of tumor cell autophagy led to TAMs reprogramming from an immunosuppressive to an inflammatory phenotype. This evidence concerns the gene BECN1 and neoplasm.