PLOD2 and breast carcinoma: These results suggest that PLOD2 is an independent prognostic factor in patients with breast cancer and PLOD2 is much higher expressed in TNBC than that in non-TNBC, but the coculture results show that PLOD2 is upregulated in both TNBC and non-TNBC breast cancer cell lines following coculture with adipocytes, thus, suggesting adipocytes can facilitate pro-metastasis role in TNBC and non-TNBC via PLOD2-dependent way.