AREG and hemoglobin measurement: In conclusion, the LB and MSI groups appear to be characterized by specific genes involved in secretory processes, colon mucus barrier, and mucosal protection, whereas HB tumors show overexpression of a subset of genes typical for surface colonocytes, along with EGF signaling agonists AREG and EREG, whose upregulation might be of predictive relevance for therapeutic choices.