For example, we previously reported that the levels of GABARAPL1, a member of the ATG8 family necessary for autophagosome elongation and closure, decreased in numerous cancer cell lines and that a high expression of this gene, in a cohort of 256 samples, correlated with good prognosis in patients with breast cancers [29,30]. The gene discussed is GABARAPL1; the disease is breast carcinoma.