TMEM74 and cancer: For example, it has been recently shown that TMEM74 (Transmembrane 74) is able to induce autophagy and favor cancer cell survival via its interaction with ATG9A and ATG16L1 [32], and that a high expression of TMEM74 is linked to a decrease of patient survival in different cancers, suggesting that ATG9A together with TMEM74 would be a factor of poor prognosis.