ACOX1 and escherichia coli infection: We think that the liver likely synthesizes triglyceride for consumption by other organs, because both the mitochondrial fatty acid β-oxidation-related Cpt1a protein [39,40]) and peroxisomal fatty acid β-oxidation protein Acox1 [39,41,57] are downregulated in Mkp-1+/+ mice after E. coli infection (Figure 10).