hsa-miR-92a appeared as novel hub miR in both regulatory and co-expression network, indicating its strong functional role in PD; GBA deficiency is associated with PD, and miR-16-5p has been shown to correspond to enhanced GBA protein levels [22,33]; and both PD and HD (Huntington’s disease) are neurodegenerative and caused by protein inclusions. Here, GBA1 is linked to juvenile Huntington disease.