LRRK2 and Parkinson disease: For example, as for ribosome that is top-ranked in Table 4, ribosomal protein s15 phosphorylation was reported to mediate LRRK2 neurodegeneration in Parkinson’s disease [30] As for phagosome that was the second top-ranked, LRRK2 was reported to be a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages [31].