LRP1B and neoplasm: Neither LRP1B copy number nor tumor volume was correlated with the time at which the tumor was excised (Fig. 5B, LRP1B: r = −0.17, p-val = 0.54; Fig. 5C %volume change: r = −0.25, p-val = 0.36), i.e. tumor volume and relative subclone prevalence were each more impacted by individual-specific variations than by the total time or number of treatment cycles.