To determine if aging reprograms suppressive DCs, we compared overall CD11c+ cells (as these antigen presenting cells represent DCs) and well-described DC subsets in lymph nodes (LNs) and tumor-draining LNs (TDLNs) from young to elderly healthy and AE17 mesothelioma-bearing mice using flow cytometry (Supplementary Figures S1A–S1F). Here, ITGAX is linked to mesothelioma.